Tesamorelin

Description:

Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH), developed for use in controlled laboratory research focused on endocrine signaling and metabolic regulation. It is widely studied for its ability to stimulate pulsatile growth hormone (GH) secretion and its downstream effects on insulin-like growth factor-1 (IGF-1) pathways.

In research environments, Tesamorelin is frequently utilized to explore tissue-response mechanisms, including vascular and endothelial signaling, inflammatory mediator activity, and extracellular matrix (ECM) remodeling processes.

Mechanism of Action:

Tesamorelin binds selectively to GHRH receptors in the anterior pituitary, promoting the release of endogenous growth hormone in a physiologically relevant pattern. This activation leads to increased IGF-1 production and influences multiple downstream pathways involved in cellular growth, metabolism, and tissue repair signaling.

It is also studied for its interaction with inflammatory pathways and its potential modulatory effects on cytokine signaling and lipid metabolism.

Potential Applications Under Study:

Endocrine & GH/IGF-1 Axis Research:
Used to investigate growth hormone secretion dynamics and IGF-1 mediated signaling pathways.

Metabolic Regulation:
Explored in studies related to lipid metabolism, glucose balance, and body composition mechanisms.

Tissue Response & Repair Signaling:
Examined for its role in vascular/endothelial function, inflammatory mediators, and ECM remodeling.

Inflammation Pathway Studies:
Analyzed for its potential influence on cytokine activity and systemic inflammatory responses.

Body Composition Research:
Investigated for effects on adipose tissue distribution and metabolic efficiency in experimental models.

Scientific Details:

Peptide Class:
GHRH Analog

Molecular Formula:
C₂₂₁H₃₆₆N₇₂O₆₇S

Molecular Weight:
5135.9 g/mol

CAS Number:
218949-48-5

Purity:
≥ 98% (HPLC)

Form:
Lyophilized Peptide

Storage:

Store in a cool, dry place. Reconstitute only with bacteriostatic water under sterile laboratory conditions. Maintain stability by minimizing exposure to heat and light.

⚠️ IMPORTANT NOTICE:

This product is intended strictly for laboratory research use only. Not for human consumption, medical, veterinary, or household use. Must be handled by qualified professionals.

Age Restriction: 21+ Only