CJC-1295 (Without DAC) – 5 mg / 10 mg

Description:
CJC-1295 (without DAC) is a synthetic peptide analog of growth hormone-releasing hormone (GHRH 1-29), designed to stimulate pulsatile growth hormone (GH) secretion. Unlike the DAC-modified version, this shorter-acting form allows researchers to study natural GH release patterns and endocrine signaling dynamics with greater precision in controlled laboratory environments.

Mechanism of Action:
CJC-1295 (no DAC) binds to GHRH receptors in the anterior pituitary, triggering the release of growth hormone in a physiologically relevant pulsatile manner. This activation leads to downstream increases in insulin-like growth factor-1 (IGF-1) and supports investigation into hormonal feedback loops, receptor sensitivity, and endocrine-axis regulation.

Potential Applications Under Study:

GH / IGF-1 Modulation:
Used to study controlled stimulation of growth hormone release and its downstream IGF-1 signaling pathways.

Endocrine Axis Research:
Supports investigation into hypothalamic-pituitary interactions, including effects on gonadotropins and metabolic hormones.

Metabolic Regulation:
Explored for its influence on lipid metabolism, glucose homeostasis, and energy balance in experimental models.

Receptor Selectivity Studies:
Enables analysis of GHRH receptor binding dynamics and downstream biomarker responses.

Scientific Details:

Sequence:
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg

Molecular Formula:
C₁₅₂H₂₅₂N₄₄O₄₂

Molecular Weight:
3367.9 g/mol

CAS Number:
863288-34-0

Purity:
≥ 98% (HPLC)

Form:
Lyophilized Peptide (5 mg / 10 mg)

Storage:
Store in a cool, dry place. Reconstitute only with bacteriostatic water under sterile laboratory conditions.

⚠️ IMPORTANT NOTICE:
This product is intended for laboratory research use only. Not for human consumption, medical, veterinary, or household use. Must be handled by trained professionals.

Age Restriction: 21+ Only